• 名称: rAgitoxin-2 (K+ channel blocker)
  • 编号: MPK-009
  • 浏览次数: 49
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Origin:Leiurus quinquestriatus hebraeus (Yellow scorpion).

Source description:Recombinant,E.coli.

M.W.:4091      Purity: >98%    Effective concentration: 50pM-10nM.

Sequence:GVPINVSCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPK.

Modifications: Disulfide bonds between Cys8-Cys28, Cys14-Cys33, and Cys18-Cys35.

Molecular formula: C169H278N54O48S8.

 

Sizes:50ug, 100ug, 5 x 50ug, 5 x 100ug lyophilized powder.

 

Activity:Agitoxin-2 is a blocker of Shaker voltage-gated K+ channels as well as the mammalian homologues of Shaker.

 

References:

1. Garcia, M.L. et al. (1994) Biochemistry 33, 6834.

2. Cayabyab, F.S. et al. (2000) Eur. J. Neurosci. 12, 1949.