• 名称: rAa1 (K+ channel blocker)
  • 编号: MPK-008
  • 浏览次数: 44
  • 已销售数量:0件

QQ交流

 

Origin:Androctonus australis (Sahara scorpion).

Source description:Recombinant,E.coli.

M.W.:3868     Purity: >98%    Effective concentration: 100nM - 1uM.

Sequence:QNETNKKCQGGSCASVCRRVIGVAAGKCINGRCVCYP.

Modifications: Disulfide bonds between Cys8-Cys28, Cys13-Cys33, and Cys17-Cys35.

Molecular formula: C156H266N54O49S6.

 

Sizes:50ug, 100ug, 5 x 50ug, 5 x 100ug lyophilized powder.

 

Activity:Aa1 is blocker of A-type voltage-gated transient K+ channels of cerebellar granular cells1.2.

 

References:

1. Pisciotta, M. et al. (1998) Biochem. Biophys. Res. Comm. 242, 287.

2. Pisciotta, M. et al. (1998) Eur. Biophys. J. 27, 69.

3. Pisciotta, M. et al. (2000) Biochim. Biophys. Acta. 1468, 203.