• 名称: sβ-Pompilidotoxin (β-PMTX)
  • 编号: MPN-001
  • 浏览次数: 83
  • 已销售数量:0件

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Origin:Batozonellus maculifrons(Solitary wasp).

Source description:Synthetic peptide.

M.W.:1559    Purity: >98%    Effective concentration: 10-100 μM.

Sequence: RIKIGLFDQLSRL. Modifications: Lys13 - C-terminal amidation.

Molecular formula: C71H124N22O17.

 

Sizes:1mg ,5 x 1mg lyophilized powder.

 

Activity:β-Pompilidotoxin slows Nav channel inactivation, without changing the peak current-voltage relationship or the activation time course of the TTX-sensitive Na+ currents in the neuromuscular synapse1-3. Β-Pompilidotoxin is five times more potent than α-Pompilidotoxin1,2.

 

References:

1. Sahara, Y. et al. (2000) Eur. J. Neurosci. 12, 1961.

2. Konno, K. et al. (2000) Neurosci. Lett. 285, 29.

3. Konno, K. et al. (1998) Biochem. Biophys. Res. Commun. 250, 612.