Trypsin Protease

  • Advanced Fermentation Platforms
  • Both Prokaryotic&Eukaryotic System
  • GMP-Compliant Pharmaceutical Purity
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Trypsin

Trypsin can recognize the site of lysine or arginine in proteins, and cleave the lysine or arginine residues at the carboxyl ends. Recombinant trypsin in Morebio is expressed by Pichia pastoris and produced under GMP regulation. Our expression system is free of any animal-derived components and free from animal virus contamination.

The activity of trypsin is inhibited by serine protease inhibitors (PMSF, TLCK, benzamidine, soybean trypsin inhibitor, ovomucoid) and metal ion chelating agents (EDTA). Our recombinant trypsin activity reaches the internationally accepted activity of USP, and is superior to competitors’ products with high storage stability.

Trypsin
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Trypsin Specification

  • Protease Name: Recombinant Trypsin
  • CAS Number: 9002-07-7
  • Alternative Name: α-trypsin, β-trypsin, tryptase, acetyltrypsin, alpha-trypsin, beta-trypsin, sperm receptor hydrolase
  • Grade: Bioactive, Carrier Free, GMP
  • Nature: Recombinant
  • Host Species:  E.coli
  • Source:  E.coli recombinant expression
  • Purity:  ≥95% (SDS-PAGE gel and HPLC analyses)
  • Endotoxin:  <1.0 EU per μg
  • Form:  Lyophilized powder
  • Appearance:  White, off-withe powder
  • Molecular Weight: 23.5±2.4kDa
  • Production Method: GMP Production
Trypsin Reference

Features

  • High activity
  • High Purity: ≥95%
  • Animal free source: Free of contaminating proteases(chymotrypsin, carboxypeptidase A, viruses)
  • Free of any protease inhibitors(PMSF)

Application

  • Protein analysis
  • Protein mass spectrometry
  • Protein sequencing
  • Peptide mapping analysis
  • Cell-dissociation reagent
Trypsin
Production Service

Trypsin Production

Morebio develops our unique expression system of E.coli for recombinant secretory proteins. We are the premier company to provide a professional and comprehensive microbial expression platform. We have years of experience with specific bioproducts in different microbial systems.

Custom Protein Expression

  • Large-scale production as requested
  • Tag removal as requested
  • Post-transitional modifications
  • Downstream purification system
  • Fast turn-around time
Custom Protein Expression

Gene Expression Workflow

  • Genes Optimization&Synthesis
  • Plasmid Construction
  • Transform & Induce
  • Protein Purification and Characterization
  • Post Processing
Gene Expression

Fermentation Capability

  • Identify and optimize the suitable expression system
  • Fermentation platform with large fermentation taks, bioreactors, large-scale purification systems
  • Genetic level for target enzymes production
  • High-purity and kilogram level products
Fermentation Capability

GMP Fermentation

  • GMP cell line banking with dedicated facilities
  • GMP manufacturing from pre-clinical to commercial scale
  • Validated GMP computer system
  • Advanced quality management systems
GMP Fermentation